Atmospheric pollutants and perinatal mortality in the city of São Luís (MA): an aggregate study / Poluentes atmosféricos e mortalidade perinatal no município de São Luís (MA): um estudo agregado

Beatriz Fernanda Santos da Silva, Rômulo Cesar Rezzo Pires, Sandra de Melo Martins dos Santos, Thaís Silva dos Reis


The present study has analyzed the correlation between the exposure to air pollutants during gestation and the occurrence of perinatal death, from 2009 to 2013, in the city of São Luís, Maranhão. A retrospective ecological study was carried out with data reported in the Mortality Information System (SIM) and daily measurements of particulate matter with a diameter of less than 10 microns (PM10) and total suspended particles (PTS). Spearman's non-parametric correlation coefficient was used with a significance level of 5%. There was a significant positive correlation between the concentration of PM10 and perinatal deaths, as well as between the concentration of PM10 and the perinatal mortality coefficient. In addition, the concentration of PM10 and the number of live births were also correlated. There was a non-significant negative correlation with PTS. The results presented indirectly suggest that pregnancy exposure to certain types of air pollutants may be associated with perinatal mortality. Although the strength of association was medium rather than individual, consistent literature and biological plausibility may be important for interpreting the results described.


Perinatal deaths; Atmospheric pollutants; Aggregate study.

Texto completo:



ANDRADE, C. L. T.; SZWARCWALD, C. L.; GAMA, S. G. N.; LEAL, M. C. Desigualdades socioeconômicas do baixo peso ao nascer e da mortalidade perinatal no município do Rio de Janeiro. Cad Saude Publica,.v.20, p.44-51, 2004.

GLINIANAIA, S.V.; RANKIN, J.; BELL, R.; PLESS-MULLOLI, T.; HOWEL, D. Does particulate air pollution contribute to infant death? A systematic review. Environ Health Perspect. v.112, n.14,p.1365-70, 2004.

KANNAN, S.; MISRA, D.P.; DVONCH, J.T.; KRISHNAKUMAR, A. Exposures to airborne particulate matter and adverse perinatal outcomes: a biologically plausible mechanistic framework for exploring potential effect modification by nutrition. Environ Health Perspect. v.114, n.11,p.1636-42, 2006.

MEDEIROS, A.P.; GOUVEIA, N.; MACHADO, R.P.P.; SOUZA, M.R.; ALENCAR, G.P.; NOVAES, H.M.D. et al. Traffic-related air pollution and perinatal mortality: a case-control study. Environ Health Perspect. v.117, n.1,p.127-32, 2009.

HEALTH EFFECTS INSTITUTE. Traffic-related air pollution: a critical review of the literature on emissions, exposure, and health effects. Special report #17. Boston, MA: HEI, 2010.

NOVAES, H.M.D.; GOUVEIA, N.; MEDEIROS, A.P.P. Mortalidade perinatal e poluição do ar gerada por veículos. Revista Brasileira de Ginecologia e Obstetrícia, v.32, n.10, p.471-475, 2010.

PEREIRA, L.A.; LOOMIS, D.; CONCEIÇÃO, G.M.; BRAGA, A.L.; ARCAS, R.M.; KISHI, H.S. et al. Association between air pollution and intrauterine mortality in São Paulo, Brazil. Environ Health Perspect. v.106, n.6, p.325-9, 1998.

PERERA, F.P.; JEDRYCHOWSKI, W.; RAUH, V.; WHYATT, R.M. Molecular epidemiologic research on the effects of environmental pollutants on the fetus. Environ Health Perspect. v.107, Suppl 3, p.451-60, 1999.

NISHIOKA, D.C.; COURA, F.L.B.; PEREIRA, L.A.A. Estudo dos efeitos da poluição atmosférica na mortalidade neonatal e fetal na cidade de São Paulo, Brasil. Rev Med (São Paulo), v.79, n. (2/4), p.81-9, 2000.

LIN, C.A.; PEREIRA L.A.A.; NISHIOKA, D.C.; CONCEIÇÃO G.M.S.; BRAGA ,A.L.F; SALDIVA P.H.N. Air pollution and neonatal deaths in São Paulo, Brazil. Braz J Med Biol Res. v 37, n.5, 2004.

WORLD HEALTH ORGANIZATION. ICD-10: International statistical classification of diseases and related health problems. Geneva, Switzerland: WHO; 2011.

INIGUEZ, C.; BALLESTER, F.; ESTARLICH, M.; ESPLUGUES, A.; MURCIA, M.; LLOP, S. et al. Prenatal exposure to traffic-related air pollution and fetal growth in a cohort of pregnant women. Occup Environ Med. v.69, n.10,p.736-44, 2012.


  • Não há apontamentos.