Achados clínicos e laboratoriais da síndrome multissistêmica pós-covid em crianças: uma revisão sistemática / Clinical and laboratory findings of post-covid multisystemic syndrome in children: a systematic review

Marília Millena Remígio da Costa, Indira Sampaio Roberto, David Henrique Vieira Vilaca, Ana Carolina de Carvalho Ruela Pires

Abstract


Introdução: Globalmente, a literatura evidencia os casos de crianças previamente saudáveis com resultado prévio positivo de SARS-CoV-2 que evoluíram para uma síndrome inflamatória grave, com características semelhantes à doença de Kawasaki ou à síndrome do choque tóxico.  Com isso, o objetivo desse estudo foi identificar na literatura os achados clínicos e laboratoriais da sindrome inflamatória multissistêmica pós covid em crianças Método: Trata-se de uma revisão sistemática de literatura. Foram incluídos todos os trabalhos encontrados nas bases de dados, realizados em seres humanos, publicados nos últimos 05 anos, em português, inglês, artigos que disponibilizem seu texto completo, artigos com versão online, produções que estivessem publicadas entre os anos de 2017 a 2022, artigos sobre a achados clínicos e laboratoriais da síndrome inflamatória multissistêmica. Resultados e Discussão: Foram avaliados qualitativamente dez estudos pois tinham os seus resultados pertinentes com os objetivos do estudo sendo descritos o  nome do primeiro autor, título do artigo,  periódico, desenho do estudo, ano de publicação, local do estudo,  faixa etária,  manifestações clínicas e  achados laboratoriais. e pontuação de acordo com a pontuação STROBE. Conclusão: Com essa pesquisa buscou-se mostrar que apesar dos dados incipientes e limitados a Sindrome  Multissistêmica Pós- Covid é uma doença heterogênea e pouco frequente nas crianças, pode mimetizar algumas síndromes inflamatórias pediátricas, como doença de Kawasaki, síndrome de ativação de macrófagos e miocardite, mas apenas em um terço dos casos pode preencher critérios rigorosos.  


Keywords


covid-19, sars- cov 2, novo coronavírus, síndrome inflamatória multissistêmica em crianças, doença de kawasaki.

References


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DOI: https://doi.org/10.34119/bjhrv5n3-038

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