Overlap syndrome of systemic lupus erythematosus and systemic sclerosis in a person living with HIV: the paradox of immunodeficiency and autoimmunity coming together / Síndrome de overlap entre lupus eritematoso sistêmico e esclerose sístemica em pessoa vivendo com HIV: o paradoxo da imunodeficiência e autoimunidade

Gabriel Pacifico Seabra Nunes, Isabela Mota de Almeida, Gabriela Dalmazo Garcia Barreto, Monique Rodrigues Pereira Pinto, Hemilly da Silva Pires, Natacha Helena Uryu, Simone Ferreira de Castro Botileiro, Sandra Lucia Euzebio Ribeiro


The existence of autoimmune dysfunction in HIV/AIDS patients is intriguing. Many cases are being reported around the world of the combination of HIV with systemic autoimmune diseases. We report a case of an HIV-infected patient that presented alopecia, symmetric polyarthritis, skin thickening and raynaud’s phenomenon. Diagnosis of overlap syndrome of SS and SLE was made and treatment with prednisone, methotrexate and nifedipine started. No HIV flare was documented.


HIV, systemic sclerosis, systemic lupus erythematosus, autoimmune diseases.

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DOI: https://doi.org/10.34119/bjhrv5n3-039


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