Evidências científicas sobre o tratamento cirúrgico da queratose actínica / Scientific evidence on the surgical treatment of actinic keratosis

Michele Andreza Fidelis Siqueira, Bruna Rosa Cretella, Cendi Soares Silveira, Thaís Alves Fagundes, Flávia Silva Guimarães, Bruno Tardin de Andrade, Arthur Barata Paviato, Maria Carolina Trancoso Souza, Renata França Ferreira, Camila Alves de Andrade Pereira, Alexandre Strapasson Boechat, Welsher Braga Ribeiro Chaves, Velton Braga Ribeiro Chaves, Pedro Henrique Sulz Marx

Abstract


As queratoses actínicas são máculas, pápulas ou placas queratósicas ou escamosas resultantes da proliferação intraepidérmica de queratinócitos atípicos em resposta à exposição prolongada à radiação ultravioleta. As queratoses actínicas são uma preocupação porque a maioria dos CECs cutâneos que surgem de queratoses actínicas pré-existentes, e as queratoses actínicas que irão progredir para o CEC não podem ser distinguidas de queratoses actínicas que se resolverão espontaneamente ou persistirão, devido a esses fatores, a maioria dos estudos recomedam tratar rotineiramente as queratoses actínicas.  As opções de tratamento para queratose actínica  incluem terapias destrutivas direcionadas à lesão (por exemplo, cirurgia, crioterapia, dermoabrasão) e terapias direcionadas ao campo com medicamentos tópicos como fluorouracilimiquimod e  mebutato de ingenol, ou terapia fotodinâmica. As terapias de campo são indicadas para o tratamento de áreas com múltiplas queratoses actínicas, lesões subclínicas que não são detectadas por inspeção visual ou palpação e cancerização de campo.


Keywords


queratose actínica, tratamento, cirurgia.

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DOI: https://doi.org/10.34119/bjhrv5n3-139

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