Perfil de sensibilidade e resistência antimicrobiana de uropatógenos isolados de pacientes com cistite / Profile of sensitivity and antimicrobial resistance of uropathogens isolated from patients with cystitis

João Marcos Ranyere da Silva Rodrigues, Vanessa Silva Teles, Lucas Dias Ribeiro, Luiz Fernandes Neto, Mikhael Rodrigues Melo, Alisson Martins Oliveira

Abstract


As infecções do trato urinário (ITUs) correspondem a uma das principais causas de consultas médicas, logo a presença de bactérias na urina de pelo menos 100.000 unidades formadoras de colônia por milímetro cúbico de urina é um preditor positivo para infecções do trato urinário. As ITUs são classificadas em baixas (cistite) e altas (pielonefrite), complicadas e não complicadas. Apresentam como principais agentes etiológicos as bactérias gram negativas, sendo a Escherichia coli a mais prevalente.  Nesse sentido, o objetivo desse estudo foi identificar os microrganismos mais prevalentes associados a cistite de pacientes internados em um hospital público no município de Anápolis, caracterizar a prevalência em relação às subáreas hospitalares, assim como identificar o perfil de sensibilidade e resistência aos antimicrobianos padronizados pela unidade hospitalar. Assim, foi realizado um estudo observacional, analítico, qualiquantitativo, retrospectivo e longitudinal, com a análise de antibiogramas e prontuários de pacientes internados com cistite no período de janeiro 2016 a dezembro 2017. Os resultados mostraram que a cistite é mais prevalente em mulheres independentemente da idade, e menos frequentes nos homens, os quais apresentaram uma média de idade mais elevada. A Escherichia coli foi a bactéria de maior prevalência nas alas hospitalares, exceto na Unidade de Terapia Intensiva (UTI), em que a Klebsiela pneumoniae foi a mais prevalente. O perfil de sensibilidade variou conforme a bactéria analisada, no entanto, a maioria dos uropatógenos foram resistentes a ciprofloxacino, que configura o antibiótico mais utilizado de forma empírica para o tratamento das cistites.


Keywords


Cistite; testes de sensibilidade microbiana; antibacterianos.

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DOI: https://doi.org/10.34117/bjdv6n11-681

DOI (PDF (Português (Brasil))): https://doi.org/10.34117/bjd.v6i11.20770.g16965

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