Habenular nuclei linked with compulsion in alcoholism and obesity / Núcleos habenulares estão relacionados com compulsão no alcoolismo e obesidade

João Victor Amaro de Souza, Yasmin Catelan Mainardes, Sandra Cristina Catelan-Mainardes


Alcoholism, also known as "alcohol dependence syndrome", is a disease that develops after repeated use of alcohol, typically associated with binge eating. Obesity is the result of a combination of genetic and environmental factors. Compulsive eating is not caused by hunger or pleasure, but as a defense mechanism that prevents feelings of loneliness, failure and abandonment. The aim of the present research, of bibliographic nature, will be to discuss the relation of the habenula with the mechanism of compulsion for the consumption of alcohol and food. As a methodology, searches will be carried out in databases, in the last 10 years, in Pubmed. The descriptors "habenula", "obesity", "alcoholism" and "compulsion" will be used in articles written in English, French and Spanish. Seeking to relate the neural pathways of the habenula, with disorders triggered by excessive alcohol consumption and eating disorders, concerning the anatomical and functional aspects and the pathways of dependence. To this end, the authors propose to understand this relationship from a neurological perspective, with an emphasis on mental health, encompassing a neurobiological and social view. It is expected, with this research, to collaborate with the development of a new alternative regarding the treatment of these diseases, considering the habenula as a reference. It is hoped, with this research, to collaborate with the development of a new alternative regarding the treatment of the complication, considering the habenula as a reference, in order to promote an improvement in the quality of life and health promotion of these patients. It is hoped, with this research, to collaborate with the development of a new alternative regarding the treatment of the complication, considering the habenula as a reference, in order to promote an improvement in the quality of life and health promotion of these patients.


alcoholism, obesity, habenula, compulsion.

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DOI: https://doi.org/10.34117/bjdv8n5-298