Chemical composition and in vitro biological activities of the essential oils of the rhizomes of Zingiber officinale Roscoe and Curcuma longa L. (Zingiberaceae) / Composição química e atividades biológicas in vitro dos óleos essenciais dos rizomas de Zingiber officinale Roscoe e Curcuma longa L. (Zingiberaceae)

Authors

  • Cicera Janaine Camilo
  • Natália Kelly Gomes de Carvalho
  • Carla de Fatima Alves Nonato
  • Débora Odília Duarte Leite
  • Alexandro Rodrigues Dantas
  • Rafael Caldas Pereira
  • Fabíola Fernandes Galvão Rodrigues
  • José Galberto Martins da Costa

DOI:

https://doi.org/10.34117/bjdv6n4-084

Keywords:

Antioxidant, antibiotic modulation, essential oil.

Abstract

Zingiberofficinale Roscoe and Curcuma longa L. (Zingiberaceae) essential oils were obtained by the hydrodistillation method. The oils offered yields of 0.120% and 0.044% respectively. GC-MS analyzes allowed the identification of 11 constituents in the Curcuma longa essential oil, with major components: ar-turmerone (36.8%), ?-tumerone (32.3%) and curlone (19,2%) For the Zingiberofficinaleessential oil 19 constituents were identified, being: neral (22.9%), zingiberene (15.5%) and geranial (14.9%) the main components. The result of the toxicity test showed significant activity against Artemiasalina for both oils. The dose values required to eliminate 50% (LC50) of the larvae were 100 µg / mL for Z. officinale and 25 µg / mL for C. longa. The antioxidant activity was performed against DPPH free radical. The most significant activity was exhibited by Z. officinale with an IC50 value of 215.8 µg / mL. The antibacterial assay with Z. officinale oil showed efficacy against S. aureus and E. coli, with MIC values of ? 213.3 ?g / mL and 85.3 ?g / mL respectively. For C. longa, MIC values ? 1024 ?g / mL were observed for both bacteria tested. Modulation with aminoglycoside antibiotics showed synergism of C. longa oil combined with amikacin against S. aureus, with a decrease in MIC from 1024 ?g / mL to 14.7 ?g / mL. Meanwhile, the Zingiberofficinale oil obtained a MIC reduction to 6.7 ?g / mL, demonstrating greater efficacy. The results observed here demonstrate the biological potential of the species as cytotoxic and antimicrobial.

 

 

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Published

2020-04-06

How to Cite

Camilo, C. J., Carvalho, N. K. G. de, Nonato, C. de F. A., Leite, D. O. D., Dantas, A. R., Pereira, R. C., Rodrigues, F. F. G., & Costa, J. G. M. da. (2020). Chemical composition and in vitro biological activities of the essential oils of the rhizomes of Zingiber officinale Roscoe and Curcuma longa L. (Zingiberaceae) / Composição química e atividades biológicas in vitro dos óleos essenciais dos rizomas de Zingiber officinale Roscoe e Curcuma longa L. (Zingiberaceae). Brazilian Journal of Development, 6(4), 17766–17772. https://doi.org/10.34117/bjdv6n4-084

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