Contribution to the Chemical Study of Rivina humilis / Contribuição para o estudo químico de Rivina humilis

Autores

  • Ma. del Rosario Hernández Medel
  • Lilia Mireya Méndez Ventura
  • Abril de los Ángeles Aguilar Tirado

DOI:

https://doi.org/10.34188/bjaerv5n3-004

Palavras-chave:

Rivina humilis, Phytolaccaceae, taraxerol, espinasterol, octacosanol.

Resumo

Rivina humilis es una planta herbácea, relativamente abundante en el estado de Veracruz; se emplea, en Medicina Tradicional, para contrarrestar diversos padecimientos, como la diarrea y la mordedura de serpientes, además, de cuestiones relacionadas con los nervios, “el espanto”. De una fracción clorofórmica del extracto metanólico de hoja de esta especie, se aislaron y dilucidaron las estructuras de taraxerol, espinasterol, octacosanol y 4-hidroxicinamato de metilo.

Referências

Sandoval-Ortega MH, Siqueiros-Delgado ME. (2018). Las familias Aizoaceae, Molluginaceae y Phytolaccaceae (Caryophyllales) en el estado de Aguascalientes, México. Polibotánica, 46: 27-47.

Rzedowski J, Calderón G. (2000). Phytolaccaceae. Flora del bajío y de regiones adyacentes, 91: 1-32.

Martínez-García, J. (1984). Phytolaccaceae. Flora de Veracruz, 36: 29-34.

Biblioteca Digital de Medicina Tradicional Mexicana (BDMTM): http://www.medicinatradicionalmexicana.unam.mx/index.php. Consultado el 11 de mayo de 2022.

Salvat A, Antonnacci L, Fortunato RH, Suarez EY, Godoy HM. (2001). Screening of some plants from Northern Argentina for their antimicrobial activity. Letters in Applied Microbiology, 32: 293-297.

Alanís-Garza B A, González-González G M, Salazar-Aranda R, Waksman de Torres N, Rivas-Galindo VM. (2007). Screening of antifungal activity of plants from the northeast of Mexico. Journal of Ethnopharmacology, 114: 468-471.

Khan MI, Denny Joseph KM, Muralidhara, Ramesh HP, Giridhar P, Ravishankar GA. (2011). Acute, subacute and subchronic safety assessment of betalains rich Rivina humilis L. berry juice in rats. Food and Chemical Toxicology, 40: 3154-3157.

Strack D, Schmitt D, Reznik H, Boland W, Grotjahn L, Wray V. (1987) Humilixanthin a new etaxanthin from Rivina humilis. Phytochemistry, 26: 2285- 2287.

Khan MI, Harsha P, Giridhar P, Ravishankar GA. Pigment identification, nutritional composition, bioactivity, and in vitro cancer cell cytotoxicity of Rivina humilis L. berries, potential source of betalains. (2012). Journal of Food Science and Technology, 47: 315-23.

González-Periañez S. (2016).Contribución al estudio químico del extracto etanólico de la raíz de Rivina humilis. Tesis de Licenciatura. Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, México.

Oladoye SO, Ayodele ET, Abdul-Hammed M, Idowu OT. (2015). Characterisation and Identification of Taraxerol and Taraxer-14-en-3-one from Jatropha tanjorensis (Ellis and Saroja) Leaves. Pakistan Journal of Scientific and Industrial Research. Series A: Physical Sciences, 58(1): 46-50.

Kunkuma VL, Kaki SS, Rao BVSK, Prasad RBN, Prabhavathi Devi BLA. (2013). A simple and facile method for the synthesis of 1-octacosanol. European Journal of Lipid Science and Technology, 115: 921–927.

García-Díaz J, Escalona-Arranz J, do Carvallo M, Rojas-Vargas J, Machado-García R, Vega-Acosta J. (2015). Aislamiento y caracterización de metabolitos de hojas de Croton linearis Jacq. Revista Cubana de Química, 27(3): 289-301.

Akihisa T, Thakur S, Rosenstein U, Matsumoto T. (1986). Sterols of Cucurbitaceae: The Configurations at C-24 of 24-AikyI-Δ5-, Δ7 and Δ8-Sterols. Lipids, 21(1): 39-47.

Badreddine A, Mostafa K, Zarrouk A, Nury T, Kharrassi Y, Nasser B, Cherkaoui C, Lizard G, Samadi M. (2015). An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system. Steroids, 99(part B): 119-124.

Rodriguez JB, Gros EG, Bertoni MH, Cattaneo P. (1996). The Sterols of Cucurbita moschata ("calabacita") Seed Oil. Lipids, 31(11): 1205-1208.

Mahmood U, Kaul VK, Acharya R, Jirovetz L. (2003). p-coumaric acid esters from Tanacetum longifolium. Phytochemistry, 64: 851-853.

Xiong Y, Deng K-Z, Guo Y-Q, Gao W-Y, Zhang T. (2009). New Chemical Constituents from the Rhizomes of Sparganium stoloniferum. Archives of Pharmacal Research, 32(5): 717-720.

Khanra R, Dewanjee S, Dua TK, Bhattacharjee N. (2017). Taraxerol, a pentacyclic triterpene from Abroma augusta leaf, attenuates acute inflammation via inhibition of NF-kB signaling. Biomedicine & Pharmacotherapy, 88: 918–923.

Berté TE, Dalmagro AP, Zimath PL, Gonçalves AE, Meyre-Silva C, Bürger C, Weber CJ, dos Santos DA, Cechinel-Filho V, de Souza MM. (2018). Taraxerol as a possible therapeutic agent on memory impairments and Alzheimer’s disease: Effects against scopolamine and streptozotocin-induced cognitive dysfunctions. Steroids, 132: 5-11.

Mus AS, Goh LPW, Marbawi H, Gansau JA. (2022). The Biosynthesis and Medicinal Properties of Taraxerol. Biomedicines, 10: 807. https://doi.org/ 10.3390/biomedicines10040807

Coballase-Urrutia E, Pedraza-Chaverri J, Camacho-Carranza R, Cárdenas-Rodríguez N, Huerta-Gertrudis B, Medina-Campos ON, Mendoza-Cruz M, Delgado-Lamas G, Espinosa-Aguirre J. (2010). Antioxidant activity of Heterotheca inuloides extracts and of some of its metabolites. Toxicology, 276: 41-8.

Borges F, Silva M, Córdova M, Schambach T, Pizzolatti M, Santos A. (2014). Anti-inflammatory action of hydroalcoholic extract, dichloromethane fraction and steroid α-spinasterol from Polygala sabulosa in LPS-induced peritonitis in mice. Journal of Ethnopharmacology, 151: 144–50.

Klein LC, Gandolfi RB, Santin JR, Lemos M, Cechinel-Filho V, de Andrade SF. (2010). Antiulcerogenic activity of extract, fractions, and some compounds obtained from Polygala cyparissias St. Hillaire&Moquin (Polygalaceae). Naunyn-Schmiedeberg's. Archives of Pharmacology, 381:121–6.

Klein LC, Meira NA, Bresolin TM, Cechinel-Filho V, Quintao NL. (2012). Antihyperalgesic activity of the methanol extract and some constituents obtained from Polygala cyparissias (Polygalaceae). Basic Clinical Pharmacology and Toxicology, 111(3):145-53.

Socala K, Nieoczym D, Pieróg M, Wlaz P. (2015). α-Spinasterol, a TRPV1 receptor antagonist, elevates the seizure threshold in three acute seizure tests in mice. Journal of Neural Transmission, 122:1239–47.

Trevisan G, Rossato MF, Walker CI, Klafke JZ, Rosa F, Oliveira SM, Tonello R, Guerra GP, Boligon AA, Zanon RB, Athayde ML, Ferreira J. (2012). Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties. Journal of Pharmacology and Experimental Therapeutics, 343(2):258-69.

Socala K, Wláz P. (2016). Evaluation of the antidepressant- and anxiolytic-like activity of α-spinasterol, a plant derivative with TRPV1 antagonistic effects, in mice. Behavioural Brain Research, 33: 19–25.

Taylor JC, Rapport L, Lockwood GB. (2003). Octacosanol in human health. Nutrition, 19: 192–195.

Guo T, Lin Q, Li X, Nie Y, Wang L, Shi L, Xu W, Hu T, Guo T, Luo F. (2017). Octacosanol Attenuates Inflammation in Both RAW 264.7 Macrophages and a Mouse Model of Colitis. Journal of Agricultural and Food Chemistry, 65(18): 3647–3658.

Wang T, Liu Y, Yang N, Ji Ch, Chan P, Zuo P. (2010). Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mice. Neural Regeneration Research, 7(14):1080-1087.

Irmak S, Dunford NT, Milligan J. (2006). Policosanol contents of bees wax, sugar cane and wheat extracts. Food Chemistry, 95: 312–318.

García Cordero J, Sarria Ruiz B, González Rámila S, Bravo Clemente L, Mateos Briz R. (2020). Eficacia de los hidroxicinamatos y los beta-glucanos como herramientas dietéticas frente a la obesidad y sus disfunciones asociadas y su aplicación como nutracéutico. Nutrición Hospitalaria, 37(5):1061-1071.

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Publicado

2022-07-07

Edição

v. 5 n. 3 (2022)

Seção

Artigos originais

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Brazilian Journal of Animal and Environmental Research (BJAER) se reserva o direito de efetuar nos originais alterações de ordem normativa, ortográfica e gramatical, com vistas a manter o padrão culto da língua, respeitando, porém, o estilo dos autores. Os trabalhos finais não serão enviadas aos autores.