Uncommon presentations of angiofibroma in sinonasal tract: a two-case report/ Apresentações incomuns de angiofibromas no trato nasossinusal: relato de dois casos

Authors

  • Luísa Corrêa Janaú Brazilian Journals Publicações de Periódicos, São José dos Pinhais, Paraná
  • Regiane Matos Batista
  • Ana Larisse Godim Barbosa
  • Luigi Ferreira e Silva
  • Leonardo Mendes Acatauassu Nunes
  • Diego Gadelha Vaz

DOI:

https://doi.org/10.34119/bjhrv3n6-101

Keywords:

juvenile nasopharyngeal angiofibroma, JNA, extranasopharyngeal angiofibroma, ENPA, endoscopic surgery.

Abstract

Juvenile nasopharyngeal angiofibroma (JNA) are rare, histologically benign, but locally aggressive, vascular tumors of the nasopharynx that affects predominantly male adolescents, its origins from other sites is denominated extranasopharyngeal angiofibroma (ENPA), which is an even rarer entity afflicting more females and young adults, representing a diagnostic and therapeutic challenge to rhinologists. In this report we present 2 cases of similar clinical presentation, with unilateral nasal obstruction and previous episodes of nasal bleeding. One patient is a 14-year-old male with a soft-tissue mass occupying nasopharynx, middle meatus, and right nasal cavity. The second patient is a 12-year-old male with a soft-tissue lesion rising from right sphenoid sinus and obliterating right nasal cavity, obstructing ipsilateral maxillary sinus, ethmoidal cells, and frontal sinus. Both patients underwent complete endoscopic excision of the lesions, the first one recurred on sphenoid sinus and the second showed no recurrence after 2 years of post-operative follow-up. The unusual sites and presentations make these rare cases and thus worth of reporting.

References

Sarpa, J. R. & Novelly, N. J. Extranasopharyngeal Angiofibroma. Otolaryngol. Neck Surg. 101, 693–697 (1989).

Huang, R. Y., Damrose, E. J., Blackwell, K. E., Cohen, A. N. & Calcaterra, T. C. Extranasopharyngeal angiofibroma. Int. J. Pediatr. Otorhinolaryngol. 56, 59–64 (2000).

Yenigun, A., Aksoy, F., Vural, O. & Ozturan, O. Angiofibroma Localized in the Sphenoid Sinus. Case Rep. Otolaryngol. 2017, 4287293 (2017).

Goud, S., Swapna, T., Bindu3, H. & Shylaja, S. R. G. Extra Nasopharyngeal Angiofibroma Simulating a Mucocele: A New Location for the Rare Entity. J. Clin. DIAGNOSTIC Res. 11, ZD28 (2017).

Windfuhr, J. P. & Vent, J. Extranasopharyngeal angiofibroma revisited. Clin. Otolaryngol. 43, 199–222 (2018).

Windfuhr, J. P. & Remmert, S. Extranasopharyngeal angiofibroma: Etiology, incidence and management. Acta Oto-Laryngologica vol. 124 880–889 (2004).

Lerra, S., Nazir, T., Khan, N., Qadri, M. S. & Dar, N. H. A case of extranasopharyngeal angiofibroma of the ethmoid sinus: A distinct clinical entity at an unusual site. Ear, Nose Throat J. 91, (2012).

Kesarwani, A. Sphenochoanal Polyp: A Rare Entity with Review of Literature. J. Otolaryngol. Res. 8, (2017).

Al Okbi, H., Jain, R. & Al-Abri, R. Sphenochoanal polyp - Surgical review. Int. J. Pediatr. Otorhinolaryngol. Extra 5, 99–101 (2010).

S, A., C, N., S, P. & SS, D. Juvenile Nasopharyngeal Angiofibroma: A Case Report. J. Clin. DIAGNOSTIC Res. 11, (2017).

Valkov, A., Duhlenski, B. & Tsvetanova, K. Modern Approach to Juvenile Nasopharyngeal Angiofibroma: A Literature Review. Int. J. Sci. Res. 5, 2319–7064 (2013).

Liu, Z. et al. Hormonal receptors and vascular endothelial growth factor in juvenile nasopharyngeal angiofibroma: Immunohistochemical and tissue microarray analysis. Acta Otolaryngol. 135, 51–57 (2015).

Szyma?ska, A., Szyma?ski, M., Morshed, K., Czekajska-Chehab, E. & Szczerbo-Trojanowska, M. Extranasopharyngeal angiofibroma: Clinical and radiological presentation. Eur. Arch. Oto-Rhino-Laryngology 270, 655–660 (2013).

Karthikeyan, P. Extra nasopharyngeal angiofibroma of the sphenoid sinus. 6, 8–13 (2014).

Singhal, S. K., Gupta, N., Verma, H., Dass, A. & Kaur, A. Extranasopharyngeal angiofibroma: Report of two cases. Egypt. J. Ear, Nose, Throat Allied Sci. 15, 73–76 (2014).

Lund, V. J. et al. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinol. Suppl. 22, 1–143 (2010).

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Published

2020-11-24

How to Cite

JANAÚ, L. C.; BATISTA, R. M.; BARBOSA, A. L. G.; SILVA, L. F. e; NUNES, L. M. A.; VAZ, D. G. Uncommon presentations of angiofibroma in sinonasal tract: a two-case report/ Apresentações incomuns de angiofibromas no trato nasossinusal: relato de dois casos. Brazilian Journal of Health Review, [S. l.], v. 3, n. 6, p. 16871–16881, 2020. DOI: 10.34119/bjhrv3n6-101. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/20349. Acesso em: 28 mar. 2024.

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Section

Original Papers