Antimicrobial consumption in pediatric intensive care units during the first year of COVID-19 pandemic / Consumo antimicrobiano em unidades de cuidados intensivos pediátricos durante o primeiro ano da pandemia de COVID-19

Authors

  • André Ricardo Araujo da Silva
  • Monique Faitanin de Moura Porto
  • Carolina dos Santos Mendes de Oliveira
  • Maria Eduarda de Oliveira Pires
  • Rafael da Rocha Quijada dos Santos
  • Cristiane Henriques Teixeira CH
  • Cristina Vieira Souza

DOI:

https://doi.org/10.34119/bjhrv5n2-152

Keywords:

COVID 19, pediatrics, antimicrobial consumption, pediatric intensive care unit .

Abstract

Introduction: The absence of standardized treatment for critical children admitted in pediatric intensive care units (PICUs) with COVID could lead to an increase in antimicrobial consumption, as indirect effect. Aim: To describe trends of antimicrobial consumption in two PICUs before and during the COVID pandemic year.Methods: We did a retrospective study in children admitted in two PICUs of Rio de Janeiro city, between March 2019 and March 2021. The first year represented the pre-pandemic period and the last one the pandemic period. Trends of antimicrobial consumption were measured by days of therapy (DOT/1000 patient-days) and analyzed by linear regression for antibiotics, antivirals and antifungals Results: Number of patients-days in the PICU 1 was 3495 in the pre-pandemic period and 3600 in the pandemic period. The overall DOT/1000 PD of antibiotics, antivirals and antifungal was 15,308.1, 942.8 and 1,691.1, respectively in the pre-pandemic period and 13,481.5, 1,335.4 and 1,243.7, respectively in pandemic period. It was verified trend of reduction of antibiotic and antifungals and increase in antivirals consumption. Number of patients-days in the PICU 2 was 5029 in the pre-pandemic period and 4557 in the pandemic period and the overall DOT/1000 PD of antibiotics, antivirals and antifungal was 16,668.5, 1,385 and 1,966.7, respectively in the pre-pandemic period and 10,896.5, 830.7 and 677.3 in pandemic period. It was verified trend of reduction of antibiotic, antivirals and antifungals consumption. Conclusion: Trends of antimicrobial consumption reduction were verified for antibiotics and antifungals in two PICUs and reduction for antiviral in one of them

 

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Published

2022-04-03

How to Cite

SILVA, A. R. A. da; PORTO, M. F. de M.; OLIVEIRA, C. dos S. M. de; PIRES, M. E. de O.; SANTOS, R. da R. Q. dos; TEIXEIRA CH, C. H.; SOUZA, C. V. Antimicrobial consumption in pediatric intensive care units during the first year of COVID-19 pandemic / Consumo antimicrobiano em unidades de cuidados intensivos pediátricos durante o primeiro ano da pandemia de COVID-19. Brazilian Journal of Health Review, [S. l.], v. 5, n. 2, p. 5750–5757, 2022. DOI: 10.34119/bjhrv5n2-152. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/45986. Acesso em: 28 mar. 2024.

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Original Papers