Perímetro do pescoço como preditor de níveis de vitamina D em adolescentes / Perimeter of the neck as a predictor of vitamin D levels in adolescents
DOI:
https://doi.org/10.34119/bjhrv5n4-022Keywords:
adolescentes, Hipovitaminose D, obesidade, perímetro do pescoço, Vitamina D.Abstract
Objetivo: Determinar a frequência de deficiência de vitamina D e sua relação com medidas antropométricas de adiposidade em adolescentes atendidos em um ambulatório de um Hospital Universitário no Rio de Janeiro.Métodos: Estudo transversal realizado com 125 adolescentes brasileiros com idade entre 12 e 18 anos. A concentração sérica de vitamina D foi classificada como deficiente quando < 20 ng/mL. Foram realizadas medidas de peso, estatura, perímetro do pescoço, perímetro da cintura e relação cintura estatura. A correlação entre variáveis de interesse foi realizada através do coeficiente de correlação de Pearson. As análises de regressão linear indicaram associação da hipovitaminose D com a adiposidade. Todas as análises estatísticas usaram um erro alfa de 5%. Resultados: A prevalência de Hipovitaminose D foi de 41,6% e 48% dos adolescentes foram classificados como obesos. Adolescentes com deficiência de vitamina D apresentaram maior média do perímetro do pescoço e do perímetro da cintura. O perímetro do pescoço foi associado a vitamina D mesmo após análise ajustada. Conclusão: A Hipovitaminose D é altamente prevalente. O perímetro do pescoço foi associado a baixos níveis de vitamina D em adolescentes.
References
Silva JS, Pereira SE, Sobrinho CJS, Ramalho A. Obesity, related diseases and their relationship with vitamin D deficiency in adolescents. Nutr Hosp. 2016;33(4):856-864.
Bloch KV, Klein CH, Szkol M, Kuschnir MC, Abreu GA, Barufaldi LA, et al. ERICA: prevalências de hipertensão arterial e obesidade em adolescentes brasileiros. Rev Saúde Pública. 2016;50(1):1-9.
Gul A, Ozer S, Yilmaz R, Sonmezgoz E, Kasap T, Takçi Ş, et al. Association between vitamin D levels and cardiovascular risk factors in obese children and adolescents. Nutr Hosp. 2017;34:323-329.
Teixeira JS, Campos ABF, Cordeiro A, Pereira SE, Saboya CJ, Ramalho A. Vitamin D nutritional status and its relationship with metabolic changes in adolescents and adults with severe obesity. Nutr Hosp. 2018;35(4):847-853.
Rahmadhani R, Zaharan NL, Mohamed Z, Moy FM, Jalaludin MY. The associations between VDR BsmI polymorphisms and risk of vitamin D deficiency, obesity and insulin resistance in adolescents residing in a tropical country. PLoS ONE. 2017;12(6):1-14.
Wojcik M, Janus D, Kalicka-Kasperczyk A, Sztefko K, Starzyk JB. The potential impact of the hypovitaminosis D on metabolic complications in obese adolescents – Preliminary results. Ann Agric Environ Med. 2017;24(4):636-639.
Fu J, Han L, Zhao Y, Li G, Zhu Y, Li Y, et al. Vitamin D levels are associated with metabolic syndrome in Q5 adolescents and young adults: The BCAMS study. Clinical Nutrition. 2018 Sep;1-7.
Kim YS, Hwang JH, Song MR. The Association Between Vitamin D Deficiency and Metabolic Syndrome in Korean Adolescents. J Pediatr Nurs. 2018;38:7-11.
Queiroz DJM, Silva AS, Dinis AS, Carvalho AT, Araújo EPS, Neves JPR, et al. Vitamin D insufficiency/deficiency and its association with cardiometabolic risk factors in Brazilian adolescents. Nutr Hosp. 2019;36(1):142-148.
khayyatzadeh SS, Mirmousavi SJ, Fazeli M, Abasalti A, Avan A, Javandoost A, et al. High dose vitamin D supplementation is associated with an improvement in several cardio-metabolic risk factors in adolescent girls: a nine-week follow up study. Ann Clin Biochem. 2017;1-26.
Geng SS, Ma JQ, Liu SS, Zhang J, Sheng XY. Vitamin D Insufficiency and Its Association with Biochemical and Anthropometric Variables of Young Children in Rural Southwestern China. Chin Med J. 2016;129:1273-1279.
Moreira TMM, Gomes EB, Santos JC. Fatores de risco cardiovasculares em adultos jovens com hipertensão arterial e/ou diabetes mellitus. Rev Gaúcha Enferm. 2010;31(4):662-669.
Instituto Brasileiro de Geografia e Estatística. Pesquisa Nacional por Amostra de Domícilio. Rio de Janeiro. 1992; 15(1):1-73.
World Health Organization (WHO). Growth reference data for 5-19 years. The WHO reference, 2007. Acesso em 2018 Jun. Disponível em: http://www.who.int/growthref/en/.
World Health Organization (WHO). Obesity: Preventing and managing the global epidemic. Report of a WHO Consultation on Obesity. Geneva: WHO; 2000.
Kurtoglu S, Hatipoglu N, Mazicioglu MM, Kondolot M. Neck circumference as a novel parameter to determine metabolic risk factors in obese children. Eur J Clin Invest. 2012;42(6):623-630.
Fernandez JR, Redden DT, Pietrobelli A, Allison DB. Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents. J Pediatr. 2004;145(4):439-444.
Ho SY, Lam TH, Janus E D. Waist to stature ratio is more strongly associated with cardiovascular risk factors than other simple anthropometric indices. Ann Epidemiol. 2003;13(10):683-691.
Farias JCF, Lopes AS, Mota J, Hallal PC. Prática de atividade física e fatores associados em adolescentes no Nordeste do Brasil. Rev Saúde Pública. 2012;46(3):505-515.
Szklo M, Nieto FJ. Epidemiology: beyond the basics. Gaithersburg (MD): Aspen Publishers; 2000.
Peters BS, dos Santos LC, Fisberg M, Wood RJ, Martini LA. Prevalence of vitamin D insufficiency in Brazilian adolescents. Ann Nutr Metab. 2009;54(1):15-21.
Silva ACM, Cureau FV, Oliveira CL, Giannini DT, Bloch KV, Kuschnir MCC et al. Physical activity but not sedentary time is associated with vitamin D status in adolescents: study of cardiovascular risk in adolescents (ERICA). Eur J Clin Nutr. 2018;1-9.
Santos BR, Mascarenhas LP, Satler F, Boguszewski MC, Spritzer PM. Vitamin D deficiency in girls from South Brazil: a cross-sectional study on prevalence and association with vitamin D receptor gene variants. BMC Pediatr. 2012;12(62):1-7.
Rafraf M, Hasanabad SK, Jafarabadi MA. Vitamin D status and its relationship with metabolic syndrome risk factors among adolescent girls in Boukan, Iran. Public Health Nutr. 2014;17(4):803-809.
Rajan S, Weishaar T, Keller B. Weight and skin colour as predictors of vitamin D status: results of an epidemiological investigation using nationally representative data. Public Health Nutr. 2017 Jul;20(10):1857-1864.
Sawicki CM, Van Rompay MI, Au LE, Gordon CM, Sacheck JM. Sun-exposed skin color is associated with changes in serum 25-hydroxyvitamin d in racially/ethnically diverse children. J Nutr. 2016;146(4):751-757.
Bezrati I, Fradj MKB, Ouerghi N, Feki M, Chaouachi A, Kaabachi N. Vitamin D inadequacy is widespread in Tunisian active boys and is related to diet but not to adiposity or insulin resistance. Libyan J Med. 2016;11(1):1-8.
Stokic E, Kupusinac A, Tomic´-Naglic´ D, Kovacˇev Zavisˇic´ B, Mitrovic M, Smiljenic D, Soskic S. Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile. Angiology. 2015;66(3):237-243.
Al-Dabhani K, Tsilidis KK, Murphy N, Ward HA, Elliott P, Riboli E, et al. Prevalence of vitamin D deficiency and association with metabolic syndrome in a Qatari population. Nutr Diabetes. 2017;7(4):1-6.
Mousa A, Naderpoor N, Courten MPJ, Scragg R, Courten B. 25-hydroxyvitamin D is associated with adiposity and cardiometabolic risk factors in a predominantly vitamin D-deficient and overweight/obese but otherwise healthy cohort. J Steroid Biochem Mol Biol. 2017;173:258-264.
Silva CS, Zambon MP, Vasques ACJ, Rodrigues AMB, Camilo DF, Antonio MARGM, et al. Circunferência do pescoço como um novo indicador antropométrico para predição de resistência à insulina e componentes da síndrome metabólica em adolescentes: Brazilian Metabolic Syndrome Study. Rev Paul Pediatr. 2014;32(2):221-229.
Preis SR, Massaro JM, Hoffmann U, D´Agostino RB, Levy D, Robins SJ, et al. Neck Circumference as a Novel Measure of Cardiometabolic Risk: The Framingham Heart Study. J Clin Endocrinol Metab; 2010;95(8):3701–3710.
Ben-Noun L, Laor A. Relationship of neck circumference to cardiovascular risk factors. Obesity Research. 2003;11(2):226–231.
Foo LH, Zhang Q, Zhu K, Ma G, Trube A, Greenfield H, et al. Relationship between vitamin D status, body composition and physical exercise of adolescent girls in Beijing. Osteoporos Int. 2009;20(3):417-425.
Sabekova K, Krivosikova Z, Gajdos H, Podracka C. Vitamin D status in apparently healthy medication-free Slovaks: Association to blood pressure, body mass index, self-reported smoking status and physical activity. Bratisl Med J. 2016;117(12):702-709.
